Region 1
Clinched Playoff Berths: Finley-Sharon/Hope-Page and Tri-State
- Finley-Sharon/Hope-Page (6-0 region, 7-0 overall)
- Already clinched at least the #2 seed
- Clinches region title with a win
- LaMoure/Litchville-Marion (4-3 region/overall) at May-Port-CG (5-1 region/overall)
- Winner will clinch playoff berth (May-Port-CG will at least be a #2 seed with win)
- Loser clinches playoff berth with a Maple Valley/Enderlin loss
- Tri-State (5-2 region/overall)
- Already clinched at least the #3 seed
- Will be the #3 seed if May-Port-CG wins (Tri-State plays out of region this week)
Region 2
Clinched Playoff Berths: Cavalier, New Rockford-Sheyenne, and North Prairie
- New Rockford-Sheyenne (6-0 region/overall) at Cavalier (6-0 region, 7-0 overall)
- Winner of this game clinches the region title
- Loser will be the #2 seed
- St. John (4-2 region, 5-2 overall)
- Clinches playoff berth with a win
Region 3
Clinched Playoff Berths: Central McLean and Ray/Powers Lake
- Ray/Powers Lake (6-1 region/overall)
- Clinches region title with a win (see below for 3-way tie)
- Central McLean (6-1 region/overall)
- Clinches the #2 seed with a Ray/Powers Lake win AND a Mohall-Lansford-Sherwood loss (Central McLean has a bye this week)
- Surrey (4-2 region, 5-2 overall) at Mohall-Lansford-Sherwood (5-1 region, 5-2 overall)
- Mohall-Lansford-Sherwood clinches a playoff berth with a win OR a TGU loss
- Surrey clinches a playoff berth with either:
- A win AND a TGU loss
OR - A loss by 16 or fewer points (Surrey beat TGU 45-8 in Week 4 and MLS plays TGU in Week 9)
- A win AND a TGU loss
- In the event Central McLean, MLS, and Ray/Powers Lake with identical records
- #1 - Ray/Powers Lake (1-1 H2H, +9 PD)
#2 - Central McLean (1-1 H2H, -12 PD, defeated MLS)
#3 - MLS (1-1 H2H, +3 PD, lost to Central McLean)
Region 4
Clinched Playoff Berths: Beach, Grant County/Flasher, Kidder County, Linton/HMB
- Linton/HMB (6-0 region/overall)
- Already clinched at least the #3 seed
- Clinches at least the #2 seed with a win OR a Kidder County loss
- Clinches region title with a win AND a Grant County/Flasher loss
- Kidder County (5-1 region/overall) at Grant County/Flasher (5-1 region/overall)
- Kidder County clinches the #2 seed with a win
- Grant County/Flasher clinches at least the #2 seed with a win by 17 or more points